Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation

From Brede Wiki
Jump to: navigation, search
Paper (help)
Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation
Authors: Lise Gutknecht, Christian Jacob, Alexander Strobel, Claudia Kriegebaum, Johannes Muller, Yong Zeng, Christoph Markert, Andrea Escher, Jens Wendland, Andreas Reif, Rainald Mossner, Cornelius Gross, Burkhard Brocke, Klaus-Peter Lesch
Citation: The International Journal of Neuropsychopharmacology 10 (3): 309-310. 2007 June
Database(s): PubMed (PMID/17176492)
DOI: 10.1017/S1461145706007437.
Link(s):
Search
Web: Bing Google Yahoo!Google PDF
Article: BASE Google Scholar PubMed
Restricted: DTU Digital Library
Other: NIF
Services
Format: BibTeX Template from PMID
Extract:

Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation reports a personality genetics study and an association study on personality disorders on genetic polymorphisms in the Tryptophan hydroxylase-2 gene (TPH2): rs4570625, rs11178997, rs4341581 and rs4565946 and personality traits assessed with the NEO PI-R and Tridimensional Personality Questionnaire.

[edit] Subjects

Subject group #1 (help)
Healthy Germans
Subjects/♂/♀: 336 /  / 247
Age: 22.4 ±5.3 (–)
Nationality: German
Approval: define approval
Databases:

Group 1 of 336 healthy Germans were included in the study. The German group had a mean age of 22.4.

The healthy subjects were recruited at the Dresden University of Technology in connection with the study:

Alexander Strobel (2004). "Dopamine D4 receptor exon III genotype influence on the auditory evoked novelty P3". NeuroReport 15: 2411-2415.

[edit] Results

Association results with personality traits are given as logistic regression coefficients and p-values.

[edit] Critique

  1. Raw personality scores are not given.
Personal tools