Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation
|Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation|
|Authors:||Lise Gutknecht, Christian Jacob, Alexander Strobel, Claudia Kriegebaum, Johannes Muller, Yong Zeng, Christoph Markert, Andrea Escher, Jens Wendland, Andreas Reif, Rainald Mossner, Cornelius Gross, Burkhard Brocke, Klaus-Peter Lesch|
|Citation:||The International Journal of Neuropsychopharmacology 10 (3): 309-310. 2007 June|
|Web:||Bing Google Yahoo! — Google PDF|
|Article:||BASE Google Scholar PubMed|
|Restricted:||DTU Digital Library|
|Format:||BibTeX Template from PMID|
Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation reports a personality genetics study and an association study on personality disorders on genetic polymorphisms in the Tryptophan hydroxylase-2 gene (TPH2): rs4570625, rs11178997, rs4341581 and rs4565946 and personality traits assessed with the NEO PI-R and Tridimensional Personality Questionnaire.
|Subject group #1 (help)|
|Subjects/♂/♀:||336 / / 247|
|Age:||22.4 ±5.3 (–)|
Group 1 of 336 healthy Germans were included in the study. The German group had a mean age of 22.4.
The healthy subjects were recruited at the Dresden University of Technology in connection with the study:
- Alexander Strobel (2004). "Dopamine D4 receptor exon III genotype influence on the auditory evoked novelty P3". NeuroReport 15: 2411-2415.
Association results with personality traits are given as logistic regression coefficients and p-values.
- Raw personality scores are not given.